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Asymmetric synthesis of syn-propargylamines and unsaturated β-amino acids under Brønsted base catalysis
Propargylamines are important intermediates for the synthesis of polyfunctional amino derivatives and natural products and biologically active compounds. The classic method of synthesizing chiral propargylamines involves the asymmetric alkynylation of imines. Here, we report a significant advance in...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600747/ https://www.ncbi.nlm.nih.gov/pubmed/26423837 http://dx.doi.org/10.1038/ncomms9544 |