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Asymmetric synthesis of syn-propargylamines and unsaturated β-amino acids under Brønsted base catalysis

Propargylamines are important intermediates for the synthesis of polyfunctional amino derivatives and natural products and biologically active compounds. The classic method of synthesizing chiral propargylamines involves the asymmetric alkynylation of imines. Here, we report a significant advance in...

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Detalles Bibliográficos
Autores principales:	Wang, Yingcheng, Mo, Mingjie, Zhu, Kongxi, Zheng, Chao, Zhang, Hongbin, Wang, Wei, Shao, Zhihui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600747/ https://www.ncbi.nlm.nih.gov/pubmed/26423837 http://dx.doi.org/10.1038/ncomms9544

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