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Epithelial cells supply Sonic Hedgehog to the perinatal dentate gyrus via transport by platelets

Dentate neural stem cells produce neurons throughout life in mammals. Sonic hedgehog (Shh) is critical for maintenance of these cells; however, the perinatal source of Shh is enigmatic. In the present study, we examined the role of Shh expressed by hair follicles (HFs) that expand perinatally in tem...

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Detalles Bibliográficos
Autores principales: Choe, Youngshik, Huynh, Trung, Pleasure, Samuel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600762/
https://www.ncbi.nlm.nih.gov/pubmed/26457609
http://dx.doi.org/10.7554/eLife.07834