A meta-analysis of threats to valid clinical inference in preclinical research of sunitinib

Poor study methodology leads to biased measurement of treatment effects in preclinical research. We used available sunitinib preclinical studies to evaluate relationships between study design and experimental tumor volume effect sizes. We identified published animal efficacy experiments where suniti...

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Detalles Bibliográficos
Autores principales: Henderson, Valerie C, Demko, Nadine, Hakala, Amanda, MacKinnon, Nathalie, Federico, Carole A, Fergusson, Dean, Kimmelman, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Epidemiology and Global Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600817/
https://www.ncbi.nlm.nih.gov/pubmed/26460544
http://dx.doi.org/10.7554/eLife.08351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600817/
https://www.ncbi.nlm.nih.gov/pubmed/26460544
http://dx.doi.org/10.7554/eLife.08351

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