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A meta-analysis of threats to valid clinical inference in preclinical research of sunitinib
Poor study methodology leads to biased measurement of treatment effects in preclinical research. We used available sunitinib preclinical studies to evaluate relationships between study design and experimental tumor volume effect sizes. We identified published animal efficacy experiments where suniti...
Autores principales: | Henderson, Valerie C, Demko, Nadine, Hakala, Amanda, MacKinnon, Nathalie, Federico, Carole A, Fergusson, Dean, Kimmelman, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600817/ https://www.ncbi.nlm.nih.gov/pubmed/26460544 http://dx.doi.org/10.7554/eLife.08351 |
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