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Reduced binding of Pittsburgh Compound-B in areas of white matter hyperintensities

The amyloid imaging agent, Pittsburgh Compound-B, binds with high affinity to β-amyloid (Aβ) in the brain, and it is well established that PiB also shows non-specific retention in white matter (WM). However, little is known about retention of PiB in areas of white matter hyperintensities (WMH), abno...

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Detalles Bibliográficos
Autores principales: Goodheart, A.E., Tamburo, E., Minhas, D., Aizenstein, H.J., McDade, E., Snitz, B.E., Price, J.C., Mathis, C.A., Lopez, O.L., Klunk, W.E., Cohen, A.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600857/
https://www.ncbi.nlm.nih.gov/pubmed/26594630
http://dx.doi.org/10.1016/j.nicl.2015.09.009