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A probabilistic model of human variability in physiology for future application to dose reconstruction and QIVIVE
The risk assessment of environmental chemicals and drugs is undergoing a paradigm shift in approach which seeks the full replacement of animal testing with high throughput, mechanistic, in vitro systems. This new approach will be reliant on the measurement in vitro, of concentration-dependent respon...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600921/ https://www.ncbi.nlm.nih.gov/pubmed/26528180 http://dx.doi.org/10.3389/fphar.2015.00213 |