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The broad-spectrum antiviral favipiravir protects guinea pigs from lethal Lassa virus infection post-disease onset

With up to 500,000 infections annually, Lassa virus (LASV), the cause of Lassa fever, is one of the most prevalent etiological agents of viral hemorrhagic fever (VHF) in humans. LASV is endemic in several West African countries with sporadic cases and prolonged outbreaks observed most commonly in Si...

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Detalles Bibliográficos
Autores principales: Safronetz, David, Rosenke, Kyle, Westover, Jonna B., Martellaro, Cynthia, Okumura, Atsushi, Furuta, Yousuke, Geisbert, Joan, Saturday, Greg, Komeno, Takashi, Geisbert, Thomas W., Feldmann, Heinz, Gowen, Brian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600983/
https://www.ncbi.nlm.nih.gov/pubmed/26456301
http://dx.doi.org/10.1038/srep14775