Structure of importin-α bound to a non-classical nuclear localization signal of the influenza A virus nucleoprotein

A non-classical nuclear localization signal (ncNLS) of influenza A virus nucleoprotein (NP) is critical for nuclear import of viral genomic RNAs that transcribe and replicate in the nucleus of infected cells. Here we report a 2.3 Å resolution crystal structure of mouse importin-α1 in complex with NP...

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Detalles Bibliográficos
Autores principales: Nakada, Ryohei, Hirano, Hidemi, Matsuura, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601014/
https://www.ncbi.nlm.nih.gov/pubmed/26456934
http://dx.doi.org/10.1038/srep15055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601014/
https://www.ncbi.nlm.nih.gov/pubmed/26456934
http://dx.doi.org/10.1038/srep15055

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