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Structural Analysis of the Pin1-CPEB1 interaction and its potential role in CPEB1 degradation

The Cytoplasmic Polyadenylation Element Binding proteins are RNA binding proteins involved in the translational regulation of mRNA. During cell cycle progression, CPEB1 is labeled for degradation by phosphorylation-dependent ubiquitination by the SCF(β−TrCP) ligase. The peptidyl-prolyl isomerase Pin...

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Detalles Bibliográficos
Autores principales: Schelhorn, Constanze, Martín-Malpartida, Pau, Suñol, David, Macias, Maria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601027/
https://www.ncbi.nlm.nih.gov/pubmed/26456073
http://dx.doi.org/10.1038/srep14990