Cargando…

Structural Analysis of the Pin1-CPEB1 interaction and its potential role in CPEB1 degradation

The Cytoplasmic Polyadenylation Element Binding proteins are RNA binding proteins involved in the translational regulation of mRNA. During cell cycle progression, CPEB1 is labeled for degradation by phosphorylation-dependent ubiquitination by the SCF(β−TrCP) ligase. The peptidyl-prolyl isomerase Pin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schelhorn, Constanze, Martín-Malpartida, Pau, Suñol, David, Macias, Maria J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601027/ https://www.ncbi.nlm.nih.gov/pubmed/26456073 http://dx.doi.org/10.1038/srep14990

Ejemplares similares

RNA recognition and self-association of CPEB4 is mediated by its tandem RRM domains
por: Schelhorn, Constanze, et al.
Publicado: (2014)

Cpeb1 expression is post‐transcriptionally regulated by AUF1, CPEB1, and microRNAs
por: Oe, Souichi, et al.
Publicado: (2021)

mRNA spindle localization and mitotic translational regulation by CPEB1 and CPEB4
por: Pascual, Rosa, et al.
Publicado: (2021)

Knockdown of CPEB1 and CPEB4 Inhibits Scar Formation via Modulation of TAK1 and SMAD Signaling
por: Cui, Hui Song, et al.
Publicado: (2023)

CPEB2, CPEB3 and CPEB4 are coordinately regulated by miRNAs recognizing conserved binding sites in paralog positions of their 3′-UTRs
por: Morgan, Marcos, et al.
Publicado: (2010)

Comparative in Silico Analyses of Cpeb1–4 with Functional Predictions
por: Wang, Xiang-Ping, et al.
Publicado: (2010)

CPEB1 mediates hepatocellular carcinoma cancer stemness and chemoresistance
por: Xu, Min, et al.
Publicado: (2018)

Cytoplasmic Polyadenylation Element Binding Proteins CPEB1 and CPEB3 Regulate the Translation of FosB and Are Required for Maintaining Addiction-Like Behaviors Induced by Cocaine
por: Drisaldi, Bettina, et al.
Publicado: (2020)

Inhibition of CPEB3 ribozyme elevates CPEB3 protein expression and polyadenylation of its target mRNAs, and enhances object location memory
por: Chen, Claire C., et al.
Publicado: (2023)

CPEB1 Mediates Epithelial-to-Mesenchyme Transition and Breast Cancer Metastasis
por: Nagaoka, Kentaro, et al.
Publicado: (2015)

Oppositional poly(A) tail length regulation by FMRP and CPEB1
por: Shin, Jihae, et al.
Publicado: (2022)

CPEB3 is Associated with Human Episodic Memory
por: Vogler, Christian, et al.
Publicado: (2009)

Expression of CPEB4 in Human Glioma and Its Correlations With Prognosis
por: Hu, Wanming, et al.
Publicado: (2015)

ApCPEB4, a non-prion domain containing homolog of ApCPEB, is involved in the initiation of long-term facilitation
por: Lee, Seung-Hee, et al.
Publicado: (2016)

Regulation of Adult CNS Axonal Regeneration by the Post-transcriptional Regulator Cpeb1
por: Lou, Wilson Pak-Kin, et al.
Publicado: (2018)

Macrophage inflammation resolution requires CPEB4-directed offsetting of mRNA degradation
por: Suñer, Clara, et al.
Publicado: (2022)

RNA binding protein CPEB1 remodels host and viral RNA landscapes
por: Batra, Ranjan, et al.
Publicado: (2016)

CPEB1 directs muscle stem cell activation by reprogramming the translational landscape
por: Zeng, Wenshu, et al.
Publicado: (2022)

CPEB2 Suppresses Hepatocellular Carcinoma Epithelial–Mesenchymal Transition and Metastasis through Regulating the HIF-1α/miR-210-3p/CPEB2 Axis
por: You, Ran, et al.
Publicado: (2023)

The role of CPEB family proteins in the nervous system function in the norm and pathology
por: Kozlov, Eugene, et al.
Publicado: (2021)

MicroRNA-122 ameliorates corneal allograft rejection through the downregulation of its target CPEB1
por: Wang, Ting, et al.
Publicado: (2017)

MicroRNA-122 ameliorates corneal allograft rejection through the downregulation of its target CPEB1
por: Wang, Ting, et al.
Publicado: (2017)

CPEB3 Deficiency Elevates TRPV1 Expression in Dorsal Root Ganglia Neurons to Potentiate Thermosensation
por: Fong, Sitt Wai, et al.
Publicado: (2016)

Expression of CPEB4 in invasive ductal breast carcinoma and its prognostic significance
por: Sun, Hao-Ting, et al.
Publicado: (2015)

Genetic and Acute CPEB Depletion Ameliorate Fragile X Pathophysiology
por: Udagawa, Tsuyoshi, et al.
Publicado: (2013)

Biphasic and Stage-Associated Expression of CPEB4 in Hepatocellular Carcinoma
por: Tsai, Li-Yun, et al.
Publicado: (2016)

A Combinatorial Code for CPEB-Mediated c-myc Repression
por: Ogami, Koichi, et al.
Publicado: (2023)

CPEB1 modulates differentiation of glioma stem cells via downregulation of HES1 and SIRT1 expression
por: Yin, Jinlong, et al.
Publicado: (2014)

The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB
por: Kandel, Eric R
Publicado: (2012)

CPEB1 deletion is not a common explanation for premature ovarian insufficiency in a Chinese cohort
por: Jiao, Wenlin, et al.
Publicado: (2020)

CPEB1-dependent disruption of the mRNA translation program in oocytes during maternal aging
por: Takahashi, Nozomi, et al.
Publicado: (2023)

Evolution of CPEB4 Dynamics Across its Liquid–Liquid Phase Separation Transition
por: Seal, Manas, et al.
Publicado: (2021)

Control of immediate early gene expression by CPEB4-repressor complex-mediated mRNA degradation
por: Poetz, Fabian, et al.
Publicado: (2022)

Secondary structure confirmation and localization of Mg(2+) ions in the mammalian CPEB3 ribozyme
por: Skilandat, Miriam, et al.
Publicado: (2016)

CPEB2 Is Necessary for Proper Porcine Meiotic Maturation and Embryonic Development
por: Prochazkova, Barbora, et al.
Publicado: (2018)

Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers
por: Pérez-Guijarro, Eva, et al.
Publicado: (2016)

Role of CPEB3 protein in learning and memory: new insights from synaptic plasticity
por: Qu, Wen Rui, et al.
Publicado: (2020)

New Phosphospecific Antibody Reveals Isoform-Specific Phosphorylation of CPEB3 Protein
por: Kaczmarczyk, Lech, et al.
Publicado: (2016)

Altered splicing leads to reduced activation of CPEB3 in high-grade gliomas
por: Skubal, Magdalena, et al.
Publicado: (2016)

NPGPx modulates CPEB2-controlled HIF-1α RNA translation in response to oxidative stress
por: Chen, Po-Jen, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_0covqiugn893ql9r97ids78621