Enhancement of Selectivity of an Organometallic Anticancer Agent by Redox Modulation

[Image: see text] Combination with redox modulators can potentiate the anticancer activity and maximize the selectivity of organometallic complexes with redox-based mechanisms of action. We show that nontoxic doses of l-buthionine sulfoximine increase the selectivity of organo-Os complex FY26 for hu...

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Detalles Bibliográficos
Autores principales: Romero-Canelón, Isolda, Mos, Magdalena, Sadler, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601049/
https://www.ncbi.nlm.nih.gov/pubmed/26397305
http://dx.doi.org/10.1021/acs.jmedchem.5b00655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601049/
https://www.ncbi.nlm.nih.gov/pubmed/26397305
http://dx.doi.org/10.1021/acs.jmedchem.5b00655

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