A Single α Helix Drives Extensive Remodeling of the Proteasome Lid and Completion of Regulatory Particle Assembly

Most short-lived eukaryotic proteins are degraded by the proteasome. A proteolytic core particle (CP) capped by regulatory particles (RPs) constitutes the 26S proteasome complex. RP biogenesis culminates with the joining of two large subcomplexes, the lid and base. In yeast and mammals, the lid appe...

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Detalles Bibliográficos
Autores principales: Tomko, Robert J., Taylor, David W., Chen, Zhuo A., Wang, Hong-Wei, Rappsilber, Juri, Hochstrasser, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601081/
https://www.ncbi.nlm.nih.gov/pubmed/26451487
http://dx.doi.org/10.1016/j.cell.2015.09.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601081/
https://www.ncbi.nlm.nih.gov/pubmed/26451487
http://dx.doi.org/10.1016/j.cell.2015.09.022

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