Schmutzi: estimation of contamination and endogenous mitochondrial consensus calling for ancient DNA

Ancient DNA is typically highly degraded with appreciable cytosine deamination, and contamination with present-day DNA often complicates the identification of endogenous molecules. Together, these factors impede accurate assembly of the endogenous ancient mitochondrial genome. We present schmutzi, a...

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Detalles Bibliográficos
Autores principales: Renaud, Gabriel, Slon, Viviane, Duggan, Ana T., Kelso, Janet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601135/
https://www.ncbi.nlm.nih.gov/pubmed/26458810
http://dx.doi.org/10.1186/s13059-015-0776-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601135/
https://www.ncbi.nlm.nih.gov/pubmed/26458810
http://dx.doi.org/10.1186/s13059-015-0776-0

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