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Schmutzi: estimation of contamination and endogenous mitochondrial consensus calling for ancient DNA
Ancient DNA is typically highly degraded with appreciable cytosine deamination, and contamination with present-day DNA often complicates the identification of endogenous molecules. Together, these factors impede accurate assembly of the endogenous ancient mitochondrial genome. We present schmutzi, a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601135/ https://www.ncbi.nlm.nih.gov/pubmed/26458810 http://dx.doi.org/10.1186/s13059-015-0776-0 |