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DNA double-strand break repair is impaired in presenescent Syrian hamster fibroblasts

BACKGROUND: Studies of DNA damage response are critical for the comprehensive understanding of age-related changes in cells, tissues and organisms. Syrian hamster cells halt proliferation and become presenescent after several passages in standard conditions of cultivation due to what is known as «cu...

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Detalles Bibliográficos
Autores principales: Solovjeva, Ljudmila, Firsanov, Denis, Vasilishina, Anastasia, Chagin, Vadim, Pleskach, Nadezhda, Kropotov, Andrey, Svetlova, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601148/
https://www.ncbi.nlm.nih.gov/pubmed/26458748
http://dx.doi.org/10.1186/s12867-015-0046-4