Engineering enhanced protein disaggregases for neurodegenerative disease

Protein misfolding and aggregation underpin several fatal neurodegenerative diseases, including Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD). There are no treatments that directly antagonize the protein-misfolding events that cause these disor...

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Detalles Bibliográficos
Autores principales: Jackrel, Meredith E, Shorter, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601286/
https://www.ncbi.nlm.nih.gov/pubmed/25738979
http://dx.doi.org/10.1080/19336896.2015.1020277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601286/
https://www.ncbi.nlm.nih.gov/pubmed/25738979
http://dx.doi.org/10.1080/19336896.2015.1020277

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