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Purification of nuclear localization signal-containing proteins and its application to investigation of the mechanisms of the cell division cycle
The GTP bound form of the Ran GTPase (RanGTP) in the nucleus promotes nuclear import of the proteins bearing nuclear localization signals (NLS). When nuclear envelopes break down during mitosis, RanGTP is locally produced around chromosomes and drives the assembly of the spindle early in mitosis and...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601338/ https://www.ncbi.nlm.nih.gov/pubmed/25862163 http://dx.doi.org/10.4161/21541248.2014.978162 |