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Hsp40 function in yeast prion propagation: Amyloid diversity necessitates chaperone functional complexity

Yeast prions are heritable protein-based elements, most of which are formed of amyloid aggregates that rely on the action of molecular chaperones for transmission to progeny. Prions can form distinct amyloid structures, known as ‘strains’ in mammalian systems, that dictate both pathological progress...

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Detalles Bibliográficos
Autores principales: Sporn, Zachary A, Hines, Justin K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601347/
https://www.ncbi.nlm.nih.gov/pubmed/25738774
http://dx.doi.org/10.1080/19336896.2015.1020268