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Hsp40 function in yeast prion propagation: Amyloid diversity necessitates chaperone functional complexity
Yeast prions are heritable protein-based elements, most of which are formed of amyloid aggregates that rely on the action of molecular chaperones for transmission to progeny. Prions can form distinct amyloid structures, known as ‘strains’ in mammalian systems, that dictate both pathological progress...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601347/ https://www.ncbi.nlm.nih.gov/pubmed/25738774 http://dx.doi.org/10.1080/19336896.2015.1020268 |