Multimodal fluorescence microscopy of prion strain specific PrP deposits stained by thiophene-based amyloid ligands

The disease-associated prion protein (PrP) forms aggregates which vary in structural conformation yet share an identical primary sequence. These variations in PrP conformation are believed to manifest in prion strains exhibiting distinctly different periods of disease incubation as well as regionall...

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Detalles Bibliográficos
Autores principales: Magnusson, Karin, Simon, Rozalyn, Sjölander, Daniel, Sigurdson, Christina J, Hammarström, Per, Nilsson, K Peter R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Technical Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601348/
https://www.ncbi.nlm.nih.gov/pubmed/25495506
http://dx.doi.org/10.4161/pri.29239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601348/
https://www.ncbi.nlm.nih.gov/pubmed/25495506
http://dx.doi.org/10.4161/pri.29239

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