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Multimodal fluorescence microscopy of prion strain specific PrP deposits stained by thiophene-based amyloid ligands
The disease-associated prion protein (PrP) forms aggregates which vary in structural conformation yet share an identical primary sequence. These variations in PrP conformation are believed to manifest in prion strains exhibiting distinctly different periods of disease incubation as well as regionall...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601348/ https://www.ncbi.nlm.nih.gov/pubmed/25495506 http://dx.doi.org/10.4161/pri.29239 |