Cargando…

Progress towards structural understanding of infectious sheep PrP-amyloid

The still elusive structural difference of non-infectious and infectious amyloid of the mammalian prion protein (PrP) is a major pending milestone in understanding protein-mediated infectivity in neurodegenerative diseases. Preparations of PrP-amyloid proven to be infectious have never been investig...

Descripción completa

Detalles Bibliográficos
Autores principales: Müller, Henrik, Brener, Oleksandr, Andreoletti, Olivier, Piechatzek, Timo, Willbold, Dieter, Legname, Giuseppe, Heise, Henrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601355/
https://www.ncbi.nlm.nih.gov/pubmed/25482596
http://dx.doi.org/10.4161/19336896.2014.983754