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Progress towards structural understanding of infectious sheep PrP-amyloid
The still elusive structural difference of non-infectious and infectious amyloid of the mammalian prion protein (PrP) is a major pending milestone in understanding protein-mediated infectivity in neurodegenerative diseases. Preparations of PrP-amyloid proven to be infectious have never been investig...
Autores principales: | Müller, Henrik, Brener, Oleksandr, Andreoletti, Olivier, Piechatzek, Timo, Willbold, Dieter, Legname, Giuseppe, Heise, Henrike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601355/ https://www.ncbi.nlm.nih.gov/pubmed/25482596 http://dx.doi.org/10.4161/19336896.2014.983754 |
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