The dynamics of Rho GTPase signaling and implications for targeting cancer and the tumor microenvironment

Numerous large scale genomics studies have demonstrated that cancer is a molecularly heterogeneous disease, characterized by acquired changes in the structure and DNA sequence of tumor genomes. More recently, the role of the equally complex tumor microenvironment in driving the aggressiveness of thi...

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Detalles Bibliográficos
Autores principales: Pajic, Marina, Herrmann, David, Vennin, Claire, Conway, James RW, Chin, Venessa T, Johnsson, Anna-Karin E, Welch, Heidi CE, Timpson, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Rho GTPase as pathogen targets; therapeutic perspectives: Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601362/
https://www.ncbi.nlm.nih.gov/pubmed/26103062
http://dx.doi.org/10.4161/21541248.2014.973749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601362/
https://www.ncbi.nlm.nih.gov/pubmed/26103062
http://dx.doi.org/10.4161/21541248.2014.973749

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