In vivo dynamics of skeletal muscle Dystrophin in zebrafish embryos revealed by improved FRAP analysis

Dystrophin forms an essential link between sarcolemma and cytoskeleton, perturbation of which causes muscular dystrophy. We analysed Dystrophin binding dynamics in vivo for the first time. Within maturing fibres of host zebrafish embryos, our analysis reveals a pool of diffusible Dystrophin and comp...

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Detalles Bibliográficos
Autores principales: Bajanca, Fernanda, Gonzalez-Perez, Vinicio, Gillespie, Sean J, Beley, Cyriaque, Garcia, Luis, Theveneau, Eric, Sear, Richard P, Hughes, Simon M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601390/
https://www.ncbi.nlm.nih.gov/pubmed/26459831
http://dx.doi.org/10.7554/eLife.06541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601390/
https://www.ncbi.nlm.nih.gov/pubmed/26459831
http://dx.doi.org/10.7554/eLife.06541

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