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Integration of the Rac1- and actin-binding properties of Coronin-1C

The coronin family of actin-binding proteins regulate actin branching by inhibiting Arp2/3. We recently reported 2 interactions that were unique to coronin-1C: binding of a Rac1 inhibitor, RCC2, to the unique linker region and Rac1 itself to the propeller domain in a manner that differs from that pr...

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Detalles Bibliográficos
Autores principales: Tilley, Frances C, Williamson, Rosalind C, Race, Paul R, Rendall, Thomas C, Bass, Mark D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601492/
https://www.ncbi.nlm.nih.gov/pubmed/25862165
http://dx.doi.org/10.4161/21541248.2014.992259