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Regulation and function of P-Rex family Rac-GEFs

The P-Rex family are Dbl-type guanine-nucleotide exchange factors for Rac family small G proteins. They are distinguished from other Rac-GEFs through their synergistic mode of activation by the lipid second messenger phosphatidyl inositol (3,4,5) trisphosphate and the Gβγ subunits of heterotrimeric...

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Detalles Bibliográficos
Autor principal: Welch, Heidi CE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601503/
https://www.ncbi.nlm.nih.gov/pubmed/25961466
http://dx.doi.org/10.4161/21541248.2014.973770