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New insights into structural determinants of prion protein folding and stability

Prions are the etiological agent of fatal neurodegenerative diseases called prion diseases or transmissible spongiform encephalopathies. These maladies can be sporadic, genetic or infectious disorders. Prions are due to post-translational modifications of the cellular prion protein leading to the fo...

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Detalles Bibliográficos
Autores principales: Benetti, Federico, Legname, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601514/
https://www.ncbi.nlm.nih.gov/pubmed/25746597
http://dx.doi.org/10.1080/19336896.2015.1022023