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Estimating Metabolic Fluxes Using a Maximum Network Flexibility Paradigm
MOTIVATION: Genome-scale metabolic networks can be modeled in a constraint-based fashion. Reaction stoichiometry combined with flux capacity constraints determine the space of allowable reaction rates. This space is often large and a central challenge in metabolic modeling is finding the biologicall...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601694/ https://www.ncbi.nlm.nih.gov/pubmed/26457579 http://dx.doi.org/10.1371/journal.pone.0139665 |