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Estimating Metabolic Fluxes Using a Maximum Network Flexibility Paradigm

MOTIVATION: Genome-scale metabolic networks can be modeled in a constraint-based fashion. Reaction stoichiometry combined with flux capacity constraints determine the space of allowable reaction rates. This space is often large and a central challenge in metabolic modeling is finding the biologicall...

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Detalles Bibliográficos
Autores principales:	Megchelenbrink, Wout, Rossell, Sergio, Huynen, Martijn A., Notebaart, Richard A., Marchiori, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601694/ https://www.ncbi.nlm.nih.gov/pubmed/26457579 http://dx.doi.org/10.1371/journal.pone.0139665

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