Cargando…

BC3EE2,9B, a synthetic carbazole derivative, upregulates autophagy and synergistically sensitizes human GBM8901 glioblastoma cells to temozolomide

Glioblastoma multiforme (GBM) is the most fatal form of human brain cancer. Although temozolomide (TMZ), an oral alkylating chemotherapeutic agent, improves the survival rate, the prognosis of patients with GBM remains poor. Naturally occurring carbazole alkaloids isolated from curry leaves (Murraya...

Descripción completa

Detalles Bibliográficos
Autores principales: CHEN, CHIEN-MIN, SYU, JHIH-PU, WAY, TZONG-DER, HUANG, LI-JIAU, KUO, SHENG-CHU, LIN, CHUNG-TIEN, LIN, CHIH-LI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601748/
https://www.ncbi.nlm.nih.gov/pubmed/26329365
http://dx.doi.org/10.3892/ijmm.2015.2332