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Investigating Apoptozole as a Chemical Probe for HSP70 Inhibition
The use of chemical tools to validate clinical targets has gained in popularity over recent years and the importance of understanding the activity, selectivity and mechanism of action of these compounds is well recognized. Dysregulation of the HSP70 protein family has been linked to multiple cancer...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601772/ https://www.ncbi.nlm.nih.gov/pubmed/26458144 http://dx.doi.org/10.1371/journal.pone.0140006 |