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Association of The Common CYP1A1*2C Variant (Ile462Val Polymorphism) with Chronic Myeloid Leukemia (CML) in Patients Undergoing Imatinib Therapy

OBJECTIVE: Cytochrome P450 is one of the major drug metabolizing enzyme families and its role in metabolism of cancer drugs cannot be less emphasized. The association be- tween single nucleotide polymorphisms (SNPs) in CYP1A1 and pathogenesis of chronic myeloid leukemia (CML) has been investigated i...

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Detalles Bibliográficos
Autores principales: Lakkireddy, Samyuktha, Aula, Sangeetha, AVN, Swamy, Kapley, Atya, Rao Digumarti, Raghunadha, Jamil, Kaiser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2015
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601872/
https://www.ncbi.nlm.nih.gov/pubmed/26464823