Inhibition of β-catenin–TCF1 interaction delays differentiation of mouse embryonic stem cells

The ability of mouse embryonic stem cells (mESCs) to self-renew or differentiate into various cell lineages is regulated by signaling pathways and a core pluripotency transcriptional network (PTN) comprising Nanog, Oct4, and Sox2. The Wnt/β-catenin pathway promotes pluripotency by alleviating T cell...

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Detalles Bibliográficos
Autores principales: Chatterjee, Sujash S., Saj, Abil, Gocha, Tenzin, Murphy, Matthew, Gonsalves, Foster C., Zhang, Xiaoqian, Hayward, Penelope, Akgöl Oksuz, Betül, Shen, Steven S., Madar, Aviv, Martinez Arias, Alfonso, DasGupta, Ramanuj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602028/
https://www.ncbi.nlm.nih.gov/pubmed/26459597
http://dx.doi.org/10.1083/jcb.201503017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602028/
https://www.ncbi.nlm.nih.gov/pubmed/26459597
http://dx.doi.org/10.1083/jcb.201503017

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