Prion aggregate structure in yeast cells is determined by the Hsp104-Hsp110 disaggregase machinery

Prions consist of misfolded proteins that have adopted an infectious amyloid conformation. In vivo, prion biogenesis is intimately associated with the protein quality control machinery. Using electron tomography, we probed the effects of the heat shock protein Hsp70 chaperone system on the structure...

Descripción completa

Detalles Bibliográficos
Autores principales: O’Driscoll, Jonathan, Clare, Daniel, Saibil, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602031/
https://www.ncbi.nlm.nih.gov/pubmed/26438827
http://dx.doi.org/10.1083/jcb.201505104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602031/
https://www.ncbi.nlm.nih.gov/pubmed/26438827
http://dx.doi.org/10.1083/jcb.201505104

Ejemplares similares