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Conformational coupling of integrin and Thy-1 regulates Fyn priming and fibroblast mechanotransduction

Progressive fibrosis is characterized by excessive deposition of extracellular matrix (ECM), resulting in gross alterations in tissue mechanics. Changes in tissue mechanics can further augment scar deposition through fibroblast mechanotransduction. In idiopathic pulmonary fibrosis, a fatal form of p...

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Detalles Bibliográficos
Autores principales: Fiore, Vincent F., Strane, Patrick W., Bryksin, Anton V., White, Eric S., Hagood, James S., Barker, Thomas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602038/
https://www.ncbi.nlm.nih.gov/pubmed/26459603
http://dx.doi.org/10.1083/jcb.201505007