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Conformational coupling of integrin and Thy-1 regulates Fyn priming and fibroblast mechanotransduction
Progressive fibrosis is characterized by excessive deposition of extracellular matrix (ECM), resulting in gross alterations in tissue mechanics. Changes in tissue mechanics can further augment scar deposition through fibroblast mechanotransduction. In idiopathic pulmonary fibrosis, a fatal form of p...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602038/ https://www.ncbi.nlm.nih.gov/pubmed/26459603 http://dx.doi.org/10.1083/jcb.201505007 |