APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments

Endocytosis allows cargo to enter a series of specialized endosomal compartments, beginning with early endosomes harboring Rab5 and its effector EEA1. There are, however, additional structures labeled by the Rab5 effector APPL1 whose role in endocytic transport remains unclear. It has been proposed...

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Detalles Bibliográficos
Autores principales: Kalaidzidis, Inna, Miaczynska, Marta, Brewińska-Olchowik, Marta, Hupalowska, Anna, Ferguson, Charles, Parton, Robert G., Kalaidzidis, Yannis, Zerial, Marino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602042/
https://www.ncbi.nlm.nih.gov/pubmed/26459602
http://dx.doi.org/10.1083/jcb.201311117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602042/
https://www.ncbi.nlm.nih.gov/pubmed/26459602
http://dx.doi.org/10.1083/jcb.201311117

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