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Telomerase activity promotes osteoblast differentiation by modulating IGF-signaling pathway
The contribution of deficient telomerase activity to age-related decline in osteoblast functions and bone formation is poorly studied. We have previously demonstrated that telomerase over-expression led to enhanced osteoblast differentiation of human bone marrow skeletal (stromal) stem cells (hMSC)...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602053/ https://www.ncbi.nlm.nih.gov/pubmed/26260615 http://dx.doi.org/10.1007/s10522-015-9596-6 |