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6-OHDA-Induced Changes in Parkinson`s Disease-Related Gene Expression are not Affected by the Overexpression of PGAM5 in In Vitro Differentiated Embryonic Mesencephalic Cells

LUHMES cells, a recently established line of immortalized embryonic mesencephalic cells, are the novel in vitro model for studying Parkinson’s disease (PD) and dopaminergic neuron biology. Phosphoglyceromutase 5 (PGAM5) is a mitochondrial protein involved in mitophagy, mitochondria dynamics, and oth...

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Detalles Bibliográficos
Autores principales: Stępkowski, Tomasz Maciej, Wasyk, Iwona, Grzelak, Agnieszka, Kruszewski, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602069/
https://www.ncbi.nlm.nih.gov/pubmed/25986246
http://dx.doi.org/10.1007/s10571-015-0207-5