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Codon-level information improves predictions of inter-residue contacts in proteins by correlated mutation analysis

Methods for analysing correlated mutations in proteins are becoming an increasingly powerful tool for predicting contacts within and between proteins. Nevertheless, limitations remain due to the requirement for large multiple sequence alignments (MSA) and the fact that, in general, only the relative...

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Detalles Bibliográficos
Autores principales: Jacob, Etai, Unger, Ron, Horovitz, Amnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602084/
https://www.ncbi.nlm.nih.gov/pubmed/26371555
http://dx.doi.org/10.7554/eLife.08932