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Codon-level information improves predictions of inter-residue contacts in proteins by correlated mutation analysis
Methods for analysing correlated mutations in proteins are becoming an increasingly powerful tool for predicting contacts within and between proteins. Nevertheless, limitations remain due to the requirement for large multiple sequence alignments (MSA) and the fact that, in general, only the relative...
Autores principales: | Jacob, Etai, Unger, Ron, Horovitz, Amnon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602084/ https://www.ncbi.nlm.nih.gov/pubmed/26371555 http://dx.doi.org/10.7554/eLife.08932 |
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