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Dissecting Alzheimer disease in Down syndrome using mouse models

Down syndrome (DS) is a common genetic condition caused by the presence of three copies of chromosome 21 (trisomy 21). This greatly increases the risk of Alzheimer disease (AD), but although virtually all people with DS have AD neuropathology by 40 years of age, not all develop dementia. To dissect...

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Detalles Bibliográficos
Autores principales: Choong, Xun Yu, Tosh, Justin L., Pulford, Laura J., Fisher, Elizabeth M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602094/
https://www.ncbi.nlm.nih.gov/pubmed/26528151
http://dx.doi.org/10.3389/fnbeh.2015.00268