Large-scale determination of previously unsolved protein structures using evolutionary information

The prediction of the structures of proteins without detectable sequence similarity to any protein of known structure remains an outstanding scientific challenge. Here we report significant progress in this area. We first describe de novo blind structure predictions of unprecendented accuracy we mad...

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Detalles Bibliográficos
Autores principales: Ovchinnikov, Sergey, Kinch, Lisa, Park, Hahnbeom, Liao, Yuxing, Pei, Jimin, Kim, David E, Kamisetty, Hetunandan, Grishin, Nick V, Baker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602095/
https://www.ncbi.nlm.nih.gov/pubmed/26335199
http://dx.doi.org/10.7554/eLife.09248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602095/
https://www.ncbi.nlm.nih.gov/pubmed/26335199
http://dx.doi.org/10.7554/eLife.09248

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