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Large-scale determination of previously unsolved protein structures using evolutionary information
The prediction of the structures of proteins without detectable sequence similarity to any protein of known structure remains an outstanding scientific challenge. Here we report significant progress in this area. We first describe de novo blind structure predictions of unprecendented accuracy we mad...
Autores principales: | Ovchinnikov, Sergey, Kinch, Lisa, Park, Hahnbeom, Liao, Yuxing, Pei, Jimin, Kim, David E, Kamisetty, Hetunandan, Grishin, Nick V, Baker, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602095/ https://www.ncbi.nlm.nih.gov/pubmed/26335199 http://dx.doi.org/10.7554/eLife.09248 |
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