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Physiological and pathological roles of tissue plasminogen activator and its inhibitor neuroserpin in the nervous system

Although its roles in the vascular space are most well-known, tissue plasminogen activator (tPA) is widely expressed in the developing and adult nervous system, where its activity is believed to be regulated by neuroserpin, a predominantly brain-specific member of the serpin family of protease inhib...

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Detalles Bibliográficos
Autores principales: Lee, Tet Woo, Tsang, Vicky W. K., Birch, Nigel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602146/
https://www.ncbi.nlm.nih.gov/pubmed/26528129
http://dx.doi.org/10.3389/fncel.2015.00396