Downregulation of host tryptophan–aspartate containing coat (TACO) gene restricts the entry and survival of Leishmania donovani in human macrophage model

Leishmania are obligate intracellular protozoan parasites of mammalian hosts. Promastigotes of Leishmania are internalized by macrophages and transformed into amastigotes in phagosomes, and replicate in phagolysosomes. Phagosomal maturation arrest is known to play a crucial role in the survival of p...

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Detalles Bibliográficos
Autores principales: Gogulamudi, Venkateswara Reddy, Dubey, Mohan Lal, Kaul, Deepak, Atluri, Venkata Subba Rao, Sehgal, Rakesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602155/
https://www.ncbi.nlm.nih.gov/pubmed/26528242
http://dx.doi.org/10.3389/fmicb.2015.00946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602155/
https://www.ncbi.nlm.nih.gov/pubmed/26528242
http://dx.doi.org/10.3389/fmicb.2015.00946

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