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Downregulation of host tryptophan–aspartate containing coat (TACO) gene restricts the entry and survival of Leishmania donovani in human macrophage model
Leishmania are obligate intracellular protozoan parasites of mammalian hosts. Promastigotes of Leishmania are internalized by macrophages and transformed into amastigotes in phagosomes, and replicate in phagolysosomes. Phagosomal maturation arrest is known to play a crucial role in the survival of p...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602155/ https://www.ncbi.nlm.nih.gov/pubmed/26528242 http://dx.doi.org/10.3389/fmicb.2015.00946 |