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Sequence-specific RNA Photocleavage by Single-stranded DNA in Presence of Riboflavin

Constant efforts have been made to develop new method to realize sequence-specific RNA degradation, which could cause inhibition of the expression of targeted gene. Herein, by using an unmodified short DNA oligonucleotide for sequence recognition and endogenic small molecue, vitamin B2 (riboflavin)...

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Detalles Bibliográficos
Autores principales: Zhao, Yongyun, Chen, Gangyi, Yuan, Yi, Li, Na, Dong, Juan, Huang, Xin, Cui, Xin, Tang, Zhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602204/
https://www.ncbi.nlm.nih.gov/pubmed/26461456
http://dx.doi.org/10.1038/srep15039