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Sequence-specific RNA Photocleavage by Single-stranded DNA in Presence of Riboflavin
Constant efforts have been made to develop new method to realize sequence-specific RNA degradation, which could cause inhibition of the expression of targeted gene. Herein, by using an unmodified short DNA oligonucleotide for sequence recognition and endogenic small molecue, vitamin B2 (riboflavin)...
Autores principales: | Zhao, Yongyun, Chen, Gangyi, Yuan, Yi, Li, Na, Dong, Juan, Huang, Xin, Cui, Xin, Tang, Zhuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602204/ https://www.ncbi.nlm.nih.gov/pubmed/26461456 http://dx.doi.org/10.1038/srep15039 |
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